• Image courtesy of the Feng Lab

  • Hippocampal CA1 4 days after status epilepticus in COX2 cKO. blue-cell nuclei; green-astrocytes; red-microglia. Courtesy of Dingledine lab

  • Image courtesy of the Hepler Lab

  • Image courtesy of the Pavlath Lab

  • Image courtesy of the Traynelis Lab

Department Name Changed to "Pharmacology and Chemical Biology"

Department of Pharmacology and Chemical Biology

Effective January 1, 2019, the Pharmacology Department became "The Department of Pharmacology and Chemical Biology.” The change reflects a broadening of vision: from fundamental science of drugs to tools (chemical probes) targeted to disease-related proteins.

"Traditional pharmacology examines drugs’ mechanism of action, while chemical biology is oriented toward dissecting the machinery of life using chemical probes," says department chair Haian Fu, PhD.

“This is more than just a name change,” says Vikas Sukhatme, MD, ScD, dean of the Emory University School of Medicine. “It reflects pharmacology and chemical biology’s capabilities as discovery engines connecting the medical school and university. I anticipate it will help us advance recruitment and build interdisciplinary programs.” 


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Faculty Highlights

Emory Receives Record $628 Million in External Research Funding for FY 2017 

Dr. Haian Fu

Emory's research funding from external funding agencies totaled $628 million for fiscal year 2016-2017. This marks the eighth consecutive year that research funding has exceeded $500 million. With an increase from $574.6 million in FY 2016, this total is the largest in Emory’s history. Federal agencies awarded $384 million, or more than 61% of the total, led by the NIH, with $320 million in awards. NIH funding represented more than 83% of total federal dollars awarded to Emory.

"Research funding at Emory has continued on a strong upward trajectory over the past decade due to the hard work of our dedicated research faculty, trainees, and administrative staff and the enthusiastic support for research from Emory's leadership,” says David Stephens, WHSC VP for research. Researchers in the WHSC received more than $584.8 million in FY 2017, or more than 93% of the university total, with $353.7 million in federal funding, including $307.7 million from the NIH. The medical school received $355.7 million, public health received $131.7 million, Yerkes received $79 million, and nursing received $15 million. Click here to read full story.

Dr. Ray Dingledine is Honored with the Prestigious ASPET "Robert R. Ruffolo Career Achievement Award"


Dr. Ray Dingledine

Congratulations to Dr. Ray Dingledine who was honored with the "Robert R. Ruffolo Career Achievement Award" from the American Society for Pharmacology and Experimental Therapeutics (ASPET). The Ruffolo Award was established in 2011 in recognition of the contributions made to drug discovery and development by Dr. Ruffolo. The award recognizes the scientific achievements of scientists who are at the height of their careers and who have made significant contributions to pharmacology.

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Dr. Ray Dingledine Honored for 25 Years of Leadership

The Department of Pharmacology thanks Ray for 25 years of amazing leadership! To honor Ray, a special seminar and reception were held on November 3rd, 2017.  Dr. Stephen Traynelis introduced Ray with several historical photos. Ray delivered an inspirational lecture on “From There to Here and Beyond” .  

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Emory Pharmacology alumnus, Prof. Lixin Zhang, received "WuXi App Tech 2017 Life Science and Chemistry Award"

Lixin Zhnag Award

Congratulations to Dr. Lixin Zhang! Dr. Zhang carried out his postdoctoral research in the Department of Pharmacology, Emory University School of Medicine, from 1995 to 1999 in Dr. Haian Fu’s laboratory, and now he serves as professor and Executive Director of State Key Laboratory of  Bioreactor Engineering at East China University of Science and Technology (ECUST). He was presented the 2017 Life Science and Chemistry Award-Scholar Award at the prestigious National Guest House for his outstanding research accomplishments on Avermectin’s microbial-manufacturing. He is one of 16 researchers to receive the honor this year by the WuXi AppTec.

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OncoPPi web portal launched for protein-protein interaction research community

OncoPPi Portal

The OncoPPi Portal (http://oncoppi.emory.edu) is an interactive web resource that allows users to access and explore cancer-focused protein-protein interactions that were experimentally identified in cancer cell lines. This resource combines network connectivity analysis, mutual exclusivity analysis of genomic alterations, cellular co-localization of interacting proteins, and domain-domain interactions. Estimates of PPI essentiality allow users to evaluate the functional impact of PPI disruption on cancer cell proliferation. Furthermore, connecting the OncoPPi network with the approved drugs and compounds in clinical trials enables discovery of new tumor dependencies to inform strategies to interrogate undruggable targets like tumor suppressors. The OncoPPi Portal serves as a resource for the cancer research community to facilitate discovery of cancer targets and therapeutic development. Click here to read full publication.

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