Rita Nahta, PhD

Assistant Professor

Emory University School of Medicine

Office: 1510 Clifton Rd Atlanta, GA 30322

Phone: 404-778-5018

Email: rnahta@emory.edu

Additional Contact Information

Mailing Address:

Emory University School of Medicine

Department of Pharmacology
Suite 5001 Rollins Research Building

Atlanta, Georgia 30322-3090

Education

  • PhD, Duke University, 2000
  • Postdoctoral Fellow, Harvard Medical School, 2000-2002
  • Postdoctoral Fellow, M.D. Anderson Cancer Center, 2002-2004

Biography

 2004-2007, Instructor, Department of Breast Medical Oncology, Division of Cancer Medicine, UT M.D. Anderson Cancer Center, University of Texas, Houston, TX

 2007-present, Assistant Professor, Department of Pharmacology, Emory University School of Medicine

 2007-present, Assistant Professor, Department of Hematology & Medical Oncology, Emory University School of Medicine

 2007-present, Molecular & Systems Pharmacology PhD Program, Graduate Division of Biomedical and Biological Sciences, Emory University

 2007-present, Winship Cancer Institute, Cancer Cell Biology Program

 2007, Georgia Cancer Coalition Distinguished Scholar

 2010-2013, Executive Committee, Molecular & Systems Pharmacology PhD Program, Graduate Division of Biomedical and Biological Sciences, Emory University

 2012, American Cancer Society (ACS) Research Scholar

 2013-2015, Executive Committee, Cancer Biology PhD Program, Graduate Division of Biomedical and Biological Sciences, Emory University

 2013, Glenn Breast Cancer Research Scholar

 2014-2015, Director of Graduate Studies (DGS) and Executive Committee, Molecular & Systems Pharmacology PhD Program, Graduate Division of Biomedical and Biological Sciences, Emory University

 2014-2015, Editorial Board Member, Molecular Pharmacology

 2017-present, Editorial Board Member, Biochemical Pharmacology

 2017-present, elected to the Executive Curriculum Committee, MD Program, Emory University School of Medicine

 2017-present, Co-Chair, ACTSI & Biological Health Sciences Subcommittee, University Research Committee, Emory University


Research

Research Area:
Translational breast cancer therapeutics, resistance to targeted therapies, kinase-signaling crosstalk and disease progression

Research Interests:
Our translational therapeutics research program focuses on the molecular and cellular mechanisms of drug resistance and disease progression in breast cancer. Based on molecular profiles and histological phenotypes, breast cancer is a highly heterogeneous disease. Approval of multiple targeted therapies during the past decade have resulted in substantial improvements in treatment and survival outcomes for patients with ER-positive or HER2-overexpressing subtypes of breast cancer. However, inherent resistance or the acquisition of resistance to targeted therapies remains a major clinical concern. We integrate cellular, molecular, genetic, pharmacological, immunological, and nanotechnology methods in our goal to understand how breast cancer cells escape targeted inhibition. Ongoing research in our lab focuses on the roles of kinase-signaling crosstalk, including insulin/IGF-1R signaling, inflammatory cytokines, and mechanisms of epithelial mesenchymal transition in drug resistance, local invasion, and cancer progression. Our breast cancer research program follows a team science approach, with active collaborations involving breast pathologists, oncologists, and statisticians, with an overall goal of translating discoveries from the lab to the clinic. Ultimately, our studies seek to identify new pharmacological targets and combination drug regimens for patients with HER2-positive, triple-negative, and ER-positive breast cancers.

Biography:

 

2004-2007, Instructor, Department of Breast Medical Oncology, Division of Cancer Medicine, UT M.D. Anderson Cancer Center, University of Texas, Houston, TX

 

2007-present, Assistant Professor, Department of Pharmacology, Emory University School of Medicine

 

2007-present, Assistant Professor, Department of Hematology & Medical Oncology, Emory University School of Medicine

 

2007-present, Molecular & Systems Pharmacology PhD Program, Graduate Division of Biomedical and Biological Sciences, Emory University

 

2007-present, Winship Cancer Institute, Cancer Cell Biology Program

 

2007, Georgia Cancer Coalition Distinguished Scholar

 

2010-2013, Executive Committee, Molecular & Systems Pharmacology PhD Program, Graduate Division of Biomedical and Biological Sciences, Emory University

 

2012, American Cancer Society (ACS) Research Scholar

 

2013-2015, Executive Committee, Cancer Biology PhD Program, Graduate Division of Biomedical and Biological Sciences, Emory University

 

2013, Glenn Breast Cancer Research Scholar

 

2014-2015, Director of Graduate Studies (DGS) and Executive Committee, Molecular & Systems Pharmacology PhD Program, Graduate Division of Biomedical and Biological Sciences, Emory University

 

2014-2015, Editorial Board Member, Molecular Pharmacology

 

2017-present, Editorial Board Member, Biochemical Pharmacology

 

2017-present, elected to the Executive Curriculum Committee, MD Program, Emory University School of Medicine

 

2017-present, Co-Chair, ACTSI & Biological Health Sciences Subcommittee, University Research Committee, Emory University

 

 

Publications