Structural Models

3DMTR analysis of the iGluR receptor family, 3DMTR scores mapped onto them as a BWR color scale (pymol .pse files), along with full data tables with the full 3DMTR analysis (.xlsx files)

Structure IDStructure File (with 3DMTR coloration)Data TableComments
GluA1pse filetable

*PDB AA Sequence is GluA2, the data
shown represents the aligned GluA1 residues

Structural models as pdb files that
were used in published papers can be downloaded

GluA2pse filetable
GluA3pse filetable*PDB AA Sequence is GluA2, the data
shown represents the aligned GluA3 residues
GluA4pse filetable*PDB AA Sequence is GluA2, the data
shown represents the aligned GluA4 residues
GluD1-NTD & CBLN2pse filetable
GluD1pse filetable
GluN1/GluN2Apse filetable
GluN1/GluN2Bpse filetable
GluN1/GluN2Cpse filetable
GluN1/GluN2Dpse filetable
GluN1/GluN3Apse filetable
GluN1/GluN3Bpse filetable

Structural models as pdb files that were used in published papers can be downloaded:

GluN1/GluN2C model with PYD-106 docked into ATD-LBD pocket (Kaiser et al. Mol Pharmacol 2018) 

Hydrated GluN2A glutamate binding domain for opening/closing simulations (Wells et al., 2018)

GluN1/GluN2A modelled from GluN1/GluN2B ATD+LBD+TM (Chen et al. Mol Pharmacol 2017)

GluN1/GluN2C model with PYD-106 docked into the ATD-LBD pocket (Khatri et al. Mol Pharmacol 2014)

GluA1+C-terminal structural model (Jenkins et al. Mol Pharmacol 2014)

GluN1/GluN2D modelled on GluA2 homomeric AMPA receptor (Acker et al. Mol Pharmacol 2011)

GluN1/GluN2A modelled on GluN2A homomeric AMPA receptor (Acker et al. Mol Pharmacol 2011)

NR2A Glutamate averaged structure (Erreger et al. J Neurosci 2005)

NR2A Homoquinolinate averaged structure (Erreger et al. J Neurosci 2005)

NR2A Apo averaged structure (Erreger et al. J Neurosci 2005)